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br intracellular fluorescence intensities of
2020-08-18
intracellular fluorescence intensities of ICG and DOX in MDA-MB-231 Digitoxin versus those in MCF-7 cells, suggesting that P-Selectin and CD44 receptor interactions contribute to the enhanced cellular uptake of PMDIs in MDA-MB-231 cells. The fluorescence intensity of DOX was further increased by
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br Preparation of PTX encapsulated micelles
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2.2. Preparation of PTX-encapsulated micelles PTX-encapsulated micelles (PTX-micelles) using four kinds of alkyl di(MePEG-lactate) phosphates with different side chains were prepared. Fifty milligrams of compounds and 2.5 mg of PTX were dissolved in 10 mL of chloroform. A thin film was formed by
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b iframe width height src
2020-08-18
r> Methods: MDA-MB-231 cells, control or overexpressing Cx43, were used in this study. Proliferation and invasion assays were performed. Quantitative PCR, ELISA and western blotting were performed to assess the regulation of inflammatory mediators and other factors upon Av treatment. Immunofluoresc
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br Fig plots for each D OAR
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Fig. 3 plots for each 3D OAR separately the extent of the correc-tions made to the automated delineations versus IOV of the man-ual delineations, both quantified by ASSD, which shows that the accuracy of the automated delineation tool was better than the manual delineation variability for most OAR
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br Combined genotypes were evaluated as genotypes combinatio
2020-08-18
Combined genotypes were evaluated as genotypes combination of these two polymorphisms. A total of 9 combinations were studied and as shown in Table 3, the combination of Arg/Arg in WRAP53 and Arg/ Arg in TP53 were the most frequent combination in both cases and controls. Pairwise haplotype esti
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br biomarkers of inflammation and
2020-08-14
biomarkers of inflammation and metabolic dysregulation are limited. In particular, given that obesity has been evaluated well as a risk factor for cancer incidence and mortality, the emphasis to date has been on iden-tifying biomarkers of this association in obese individuals. Our finding suggests
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br Proctologist admission br Physical and imaging
2020-08-12
Proctologist admission - Physical and imaging exams Oncologist: CHT-5-FU/LV - Manometria Radiotherapist: RT 54Gy - Wexner scale - FIQL questionnaire Define as: surgery or follow-up 6 Weeks Staging Restaging Reapplication: Neoadjuvant treatment RT/CHT - Wexner
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Bladder neck pTa HG Traditional Papillary F
2020-08-12
Bladder neck 1 30 pTa HG Traditional Papillary 21 F 69 Former Negative No NMIBC Multifocal 5 10–10–40–30–10 pTa LG Traditional Papillary 22 M 69 Former NA Yes MIBC Left side wall 1 50 pT2 HG Traditional Papillary 23 M 70 Yes Negative Yes NMIBC Trigone 1 24 p
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br Figure In ovo efficacy
2020-08-12
Figure 3. In ovo efficacy of 8a compared to DOX after two intratumoral injections of each drug (20 nmol) twice a day for two consecutive days, white arrows indicate the tumors, scale bar: 0.5 cm. (A) left: tumor before injection of DOX; right: tumor three days post injection of DOX (50 % tumor reg
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br Extraction of VOCs From Urine Samples by Stir
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Extraction of VOCs From Urine Samples by Stir Bar Sorptive Extraction Urine samples were thawed in ice, transferred to centrifuge tubes, and centrifuged for 10 minutes at 300 g prior to extraction. To extract the organic metabolites (ie, VOCs), 1.0 mL of urine sample supernatant, 19.0 mL of DI
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br All animal experiments were conducted according to the in
2020-08-12
All animal experiments were conducted according to the institu-tional ethics and safety guidelines (Institutional Animal Welfare and Ethics Committee, First Affiliated Hospital of Bengbu medical college, Anhui, China). In total, forty 8-week-old BALB/c-Foxn1null mice were used in the experimen
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br SPSS Armonk NY USA or GraphPad
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SPSS, Armonk, NY, USA) or GraphPad Prism 6.0 (GraphPad Software, La Jolla, CA, USA). The results were presented as mean ± standard deviation (SD). Quantitative data were analyzed by two-tailed in-dependent Student's t tests and analysis of variance. Categorical vari-ables were compared using chi-s
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br Mel Rm cells were cultured in
2020-08-12
Mel-Rm 94421-68-8 were cultured in different treatment media condition. The caspase-3 activity of lysates from the cells treated was measured with the caspase activity colorimetric assay kit (Bio-techne) according to the manufacturer's protocol using a plate reader. Data were obtained from two ind
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br activate transcription of casein kinase and ER antagonist
2020-08-12
activate transcription of casein kinase 2 [69], and ER antagonists block this action. In general, MDSC are not present in healthy individuals but occur in pathologic states associated with chronic inflammation and cancer [17]. For example, BC biopsies from patients with residual disease after c
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br Jackson JG Lozano G TNBC invasion downstream of
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[10] Jackson JG, Lozano G. TNBC invasion: downstream of STAT3. Oncotarget 2017;8:20517. [11] Rajesh E, Sankari LS, Malathi L, Krupaa JR. Naturally occurring products in cancer therapy. J Pharm Bioallied Sci 2015;7(Suppl. 1):S181. [12] Demain AL, Vaishnav P. Natural products for cancer chemothera